P12.10 The ROAM / EORTC 1308 trial: Radiation versus observation following surgical resection of atypical meningioma - study update

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The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial

BACKGROUND Atypical meningiomas are an intermediate grade brain tumour with a recurrence rate of 39-58 %. It is not known whether early adjuvant radiotherapy reduces the risk of tumour recurrence and whether the potential side-effects are justified. An alternative management strategy is to perform active monitoring with magnetic resonance imaging (MRI) and to treat at recurrence. There are no r...

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Radiotherapy versus observation following surgical resection of atypical meningioma (the ROAM trial).

Kaur et al 1 have produced a timely systematic review on the role of adjuvant radiotherapy for atypical meningioma (AM) and malignant meningioma. Their review highlights the paucity of good quality prospective studies and the urgent need for prospective clinical trials for AM. Kaur et al 1 identify extent of resection (EOR) as an important prognostic factor but fail to comment on how this was d...

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Pterional versus Endoscopic Endonasal Transsphenoidal Surgery for Resection of Tuberculum Sellae ‎Meningioma: Comparative Assessment of Opthalmological and Surgical Outcomes

Objective A Comparatively study of effectiveness and safety of traditional pterional surgery (TPS) and endoscopic endonasal trans-sphenoidal suirgery (EETS) for resection of Tuberculum sellae meningioma using visual and gross total resection as outcome measures. Methods A PUBMED and MEDLINE (2002-2014) search were performed to identify the series for tuberculum sellae meningioma (TSM) resected...

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Surgical site after resection of a meningioma.

PURPOSE Our goal was to characterize MR changes over time at the site of meningioma resection in order to determine optimal timing for detecting residual and recurrent tumor. METHODS Twenty-one patients were studied with enhanced MR imaging during the first 5 postoperative days and additional studies were obtained 3 to 8 weeks after surgery (16 studies), 3 months to 1 year after surgery (17 s...

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The impact of adjuvant stereotactic radiosurgery on atypical meningioma recurrence following aggressive microsurgical resection.

OBJECT Patients with atypical meningioma often undergo gross-total resection (GTR) at initial presentation, but the role of adjuvant radiation therapy remains unclear. The increasing prevalence of stereotactic radiosurgery (SRS) in the modern neurosurgical era has led to the use of routine postoperative radiation therapy in the absence of evidence-based guidelines. This study sought to define t...

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ژورنال

عنوان ژورنال: Neuro-Oncology

سال: 2017

ISSN: 1522-8517,1523-5866

DOI: 10.1093/neuonc/nox036.368